STUDIES ON HYDROXYETHYLTHIAMINE AND RELATED COMPOUNDS:II. ACTION OF THIAMINASE ON HYDROXYALKYLTHIAMINE

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1. Investigation was made of the action of two types of bacterial thiaminase on α-hydroxyalkyl-2-thiamine (hydroxyethyl, hydroxypropyl and hydroxyisobutyl) and hydroxyethylthiamine propyl disulfide.2. While hydroxyalkylthiamine was readily decomposed by thiaminase I of Bacillus thiaminolyticus Matsukawa et Misawa, it was fairly resistant to the action of thiaminase II produced by Bacillus aneurinolyticus Kimura et Aoyama.3. Hydroxyethylthiamine propyl disulfide was remarkably resistant to both thiaminases.
日本ビタミン学会の論文