Action of Thiamine Tetrahydrofurfuryl Disulfide on the Isolated Clam Heart

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概要

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• 1. The action of thiamine tetrahydrofurfuryl disulfide (TTFD) on the excised heart of clam (Meretirx meretrix lusoria) was investigated.2. TTFD displayed a striking postive inotropic action. This action did not appear in Ca-free or Na-free solution, but appeared in K-free solution.3. TTFD antagonized the negative inotropic action of acetylcholine.4. These actions of TTFD were closely similar to those of thiamine propyl disulfide and these actions may be ascribed to -N-CHO -C-CH3=C in the structure.

• 日本ビタミン学会の論文

著者

• 篠崎 英男

  Department of Dermatology, Chiba University School of Medicine

関連論文

• Action of Thiamine Tetrahydrofurfuryl Disulfide on the Isolated Clam Heart

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