REDUCTION OF DEHYDROASCORBIC ACID WITH PYRUVATE OXIDASE SYSTEM:I. REDUCTION OF DEHYDROASCORBIC ACID IN ESHERICHIA COLI K12

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概要

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• 1. It was observed that in the medium containing E. coli K12 dehydroascorbic acid was reduced as long as pyruvate existed.2. The reduction is dependent upon a pyruvate oxidase system, but is independent of dehydroascorbic acid reductase.3. Lipoic acid, dihydrolipoic dehydrogenase and CoA were found to be essential for the reduction in the pyruvate oxidase system of the cell-free extract, using reduced NAD as the hydrogen donor, but dihydrolipoic dehydrogenase was not essential in the absence of reduced NAD.4. A plausible reaction mechanism is presented.

• 日本ビタミン学会の論文

著者

• 島薗 順雄

  Department of Biochemistry, Faculty of Medicine, University of Tokyo

• 滝口 久

  Department of Biochemistry, Nihon University School of Dentistry

関連論文

• URINARY OXALIC ACID EXCRETION BY MAN FOLLOWING INGESTION OF LARGE AMOUNTS OF ASCORBIC ACID
• THE PATTERNS OF LACTATE DEHYDROGENAE ISOENZYMES IN SCORBUTIC GUINEA PIG GINGIVA
• REDUCTION OF DEHYDROASCORBIC ACID WITH PYRUVATE OXIDASE SYSTEM:I. REDUCTION OF DEHYDROASCORBIC ACID IN ESHERICHIA COLI K12
• REDUCTION OF DEHYDROASCORBIC ACID WITH PYRUVATE OXIDASE SYSTEM:II. REDUCTION OF DEHYDROASCORBIC ACID WITH PYRUVATE OXIDASE ISOLATED FROM PIG HEART MUSCLE

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