A Case Report of the Leucemic Child with Marked Osteoarticular Symptoms and Radiological Signs

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In leukemic children, 50 to 60% can be expected to show bone change of some kind radiologically.It is reported that there are four types of lesions: transverse band, osteolysis, osteosclerosis and subperiosteal new bone formation.Among them, transverse band and osteolysis are most frequently seen (over 50%).And, it's reported that the demonstration of the narrow transverse band at the shaft ends of the long bones which is the earliest change provides valuable information for the detection of leukemia in children.Recently, we have encountered a case of leukemic child with marked osteoarticular symptoms and radiological signs.The patient was a girl 7 years of age whose upper back pain was 2 months' standing at the time of admission to the hospital and her clinical course suggested rheumatic fever and subsequently, compressional collaps of 7th & 12th thoracic spinal body was discovered.At that time, blood smears and marrow aspiration revealed no pathological findings.However, 5 months later, marked transverse zone of the proximal metalpysis of the left tibia and osteolytic lesions of the distal metaphysis of both femur appeared and inmature cells appeared in the peripheral circulation, too.So, under the diagonsis of leukemia, anti-cancerous chemotherapy was done successfully.
西日本整形・災害外科学会の論文