The Three Cases of Multiple Myeloma

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The three cases of multiple myeloma were discussed in the present paper. Their clinical examination findings were as follow;Bence-Jones protein in the urine revealed negative in all cases.These patients were admitted to the hospital due to the progressive pain of back and chest, of the weakness of lower limbs, that occured 8 to 10 months prior to admission.The first patient had suddenly an attack of paraplegia 7 weeks after hospitalization, then laminectomy of the 10-th dorsal vertebra was carried out and removed tumorous mass in this part. The mass examined micropathologically and found myeloma. He died of complication of paraplegia 14 months after onset of symptoms.It was important that, in case 2 and 3, bone marrow smear afforded diagnosis as myeloma.The second patient died 12 months after onset of symptoms.In case 3, bone pain was relieved because of medicating steroid hormone and endoxan; however destructive findings of x-ray examination was progressively increased.The third patient now living for 48 months after her troubles without complaints.When bone pain presents in eldery patients associated with some general weakness and progressive weight loss of anaemia, we emphasize, bone marrow aspiration is directed as a search for myeloma.
西日本整形・災害外科学会の論文