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A case of Paget's disease in the pelvic bone was presented here.A 46-year-old male patient was found unexpectedly a higher value of serum alkaline phosphatase, and was introduced to our clinic in order to get a proper diagnosis.His right pelvic bone which was radiopaque showed an higher up take of 99mTc in bone scintigram. Open biopsy and histological study typical findings of Paget's disease.He was treated with a porcine calcitonin. As to serum alkaline phosphatase, 45.5 K. A. unit came down to 18.9 K. A. unit by the calcitonin medication for 4 months.