Two Autopsy Cases of Metastatic Spinal Tumors

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Autopsy was performed in 2 cases of metastatic spinal tumors with complete paralysis and with non-paralysis. Histopathological findings in both cases were comparatively examined. Although all the circumference of the dura mator were infiltrated with tumors in both cases, the shape of the spinal cord was kept well without being flat-tened, and the degenerative changes to sponges in the whole white substances were characteristic. The degerative changes in the white substance were more remarkable in the case of complete paralysis than that of nonparalysis. However, the findings showing circulatory disturbance in the venous system were observed more apparently in the case of non-paralysis. Particularly in the dura mater with the finding of a lot of bleeding, the secondary changes occurred and circulatory disturbance further progressed. Thus, the spinal cord has a possibility to fall into a state of critical destruction of the tissue. In other words, during the period until falling into a complete paralysis in this disease, it is anticipated that the patent venous circulatory disturbance may progress in the spinal cord. It is quite possible that the spinal cord may have been fallen into the irreversible destruction of the tissues.
西日本整形・災害外科学会の論文