Histopathological study of the bone in the arterial occulusive disease.

概要

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We studied histopathology of the bone which is ischemic. Clinical materials were 6 cases which were amputated due to arterial occulusive diseases such as ASO, TAO and thrombosis. In those limbs the femoral head, the femoral medial condyle and the talus were examined. As the result we would stress that the early changes of the bone are detectable in fat cells or marrow cells in bone marrow, not in bone trabeculae. Especially in fat cells, disappearance of nucleus, irregular or obscure cells contour, various sizes of fat cells and microcyst formation are characteristic findings of ischemic. On the other side, in the bone trabeculae it was not possible to distinguish between living and dead whether the lacuna is empty or not. Ischemic bone changes are conspicuous in subchondral bone rather than in deeper or central part of bone.
西日本整形・災害外科学会の論文