Melorheostosis : A report of two cases.
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Two cases of melorheostosis were presented. In case 1 (8 months, boy), painless contracture and deformity of the right middle finger were the initial findings. Roentgenograms showed patchy sclerotic changes in the right upper extremity (the humerus, radius, ulna, carpi, metacarpi and pharanges). Eight years later, follow-up study indicated ranges of motion of the involved joints progressively decreased and noticeable sclerotic linear streaks which were corresponded to the C5, 6, 7 and 8 segments of a sclerotome.Another case was an 11-year-old boy who complained of painless deformity of the left second toe. X-ray examinations revealed patchy sclerosis on the left lower extremity (the acetabulum, femur, tibia, fibula, tarsi and first and second digits rays). These bony changes were corresponded to the L3, 4, 5 and 51 segments of a sclerotome.Segmental distribution of linear hyperostosis implies damages to segments of the neural crest during embryogenesis. In both cases bone scintigrams with 99mTc-MDP disclosed increased uptake in radiologically abnormal areas. These bony lesions are considered metabolically active.
- 西日本整形・災害外科学会の論文
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- Melorheostosis : A report of two cases.