Investigation of tuberculous spondylitis resistant to therapy - Report of two cases.:Report of Two Cases

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The cases who twice underwent surgery for tuberculosis of the spine are reported. Both patients received radical surgical treatment and chemotherapy with isoniazid, rifampicin and streptomycin. In the first case spondylitis recurred five months after the first operation. In the second case it recurred one month after. The tubercle bacillus of the first was found to have resistance to rifampicin, para-aminosalicylic acid and streptomycin. That of the second case was found to have resistance to rifampicin, ethanbutal, kanamycin and streptomycin.Each patient received a second operation. In the first case antituberclous drugs were changed to isoniazid, ethanbutal and kanamycin, and in the second case antituberclous drugs were changed to isoniazid and ethionamide. Both patients have recovered and are doing well with solid fusion noted.
西日本整形・災害外科学会の論文