Comparative Study between Euro-Collins Solution and UW Solution for Cold Storage of Rat Limbs.

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In order to clarify the effect of cold preservation using the UW solution for vascularized composite limb tissue, the authors performed a comparative study between the Euro-Collins and UW solutions for assessment of simple cold preservation of rat limbs in reimplantation.Thirty Lewis rat limbs were preserved at 4°C in EC solution (n=18) or UW solution (n=12) for 72 hours, and grafted orthotopically to a syngeneic rat using microsurgical techniques. We evaluated the vascular patency rate and death rate a week after surgery for both groups (EC group and UW group), and performed histological evaluation of bone, muscle, growth plate, and articular cartilage for each specimen of successful grafts in both groups.Both the vascular patency rate and the death rate between the EC group and the UW group showed no significant differences. There were no clear differences in histological viability between both groups, in all tissues.In conclusion, we could not demonstrate a protective effect of the UW solution as a cold preservation medium, as compared to the EC solution.
西日本整形・災害外科学会の論文