Two Cases of Bone Lesions Associated with Adult T-cell Leukemia(ATL) as the Primary Sites.

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We experienced two cases of bone lesions associated with ATL as the primary sites. Case 1 was a 45-year-old man who complained of right hip joint pain. Radiographically, there was an osteolytic lesion in the femoral neck. The patient was positive for HTLV-I antisera and ATL like cells were found in his peripheral blood. Biopsy of the femoral neck demonstrated a Non-Hodgkin lymphoma, diffuse pleomophic cell type. We therefore diagnosed ATL of bone origin. Case 2 was a 62-year-old man who complained of neck pain and eruption. On X-ray, C3 was compressed and biopsy of the eruption, positive HTLV-I antisera and examination of the peripheral blood all confirmed the diagnosis of ATL.Since ATL with bone lesions as the primary site is easily misdiagnosed as a metastatic tumor of unknown origin, careful diagnosis is needed in patients with bone lesions from an unknown primary site.
西日本整形・災害外科学会の論文