On the influences of various substances on the absorption of histamine in the large intestine and the mechanism of its absorption
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概要
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In case of single administration of histamine hydrochloride, histamine is not absorbed in the large intestine of rabbit, but is slightly absorbed at the high temperature as 32°C or more. In the combined administrations with various substances, the followings were noted : The absorption of histamine is not promoted by amino acids, but it is evidently promoted by <I>Para</I>-amino-benzoic acid or cattle bile. Especially the promoting action of the latter is more remarkable. Also, some of aromatic carboxylic acids promote the absorption of histamine. The influence of hypertonic or hypo. tonic enema solution containing histamine, and of prior treatments with narcotics on the histamine absorption were not evident.
- 社団法人 日本薬理学会の論文