Supplemental studies on the action of various autonomic drugs.:Report I. The effects of sympathetic denervation on the response of nictitating membranes and pupils of the cat to autonomic drugs and the peripheral action of the ganglion-blocking agents
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Responses of normal and sympathetic denervated nictitating membranes and pupils (<I>in situ</I>), and of the sphincter and dilatator iridis muscles (<I>in vitro</I>) of cat to various autonomic drugs were comparatively studied. The drugs used were adrenaline (Ad.), <I>noradrenaline</I> (NAd.), Acetylcholine (ACh), pilocarpine, atropine, hexamethonium (C<SUB>6</SUB>) and TEA. The peripheral actions of C<SUB>6</SUB> and TEA were analyzed by the effects of these drugs upon the action of Ad., NAd. and ACh. From these experimental results the innervation of nictitating membranes and pupils was discussed.
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