Influences of antituberculous substances upon respiratory gaseous metabolism in rats
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概要
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Five chemotherapeutic agents against tuberculosis were administered in comparatively large doses by stomach tube to rats or injected intramuscularly, and the respiratory gaseous metabolism of the animals was measured. The effects of the drugs appeared for the most part one hour after the administration. In a word, it can be said that sodium <I>p</I>-amino-salicylate, streptomycin sulfate, and dihydrostreptomycin sulfate should restrain the respiratory gaseous metabolism of rats and <I>p</I>-acetylaminobenzaldehyde thiosemicarbazone and <I>iso</I>nicotinic acid hydrazide should accelerate it.
- 社団法人 日本薬理学会の論文