t-π-Oxocamphovの作用機序に関する実験的研究-1・2-
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概要
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The effect of aldehydes, including <I>d-trans</I>-7-aldehyde-π-apocamphor (vitacamphor), on the activity of dehydrogenase of rat tissue homogenates and of bovine heart muscle pulp was observed. The aldehydes such as vitacamphor, 10-oxocamphor, benzaldehyde, anisaldehyde and furfural, considerably decreased the activities of dehydrogenases of the brain and heart homogenates, and of lactic and citric dehydrogenase of the heart. Vitacamphor showed less inhibitory effect on these enzymes of the kidney and liver than other aldehydes. Two aldehydes, cinnamic aldehyde and citral, caused a strong inhibition on the dehydrogenase of tissue homogenates and lactic, citric and some other dehydrogenases, while citronellal, heptaldehyde and acetaldehyde showed only slight effects on dehydrogenase activities.
- 社団法人 日本薬理学会の論文