Studies on relaxing factors in skeletal muscle

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概要

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• Chief attention of this article is focused on the differentiation between PC-dependent "relaxing factor" (PC=Phosphocreatine), identified as creatine phospho-kinase by Lorand, and ATP-dependent one, similar to or identical with Marsh-factor. Results obtained by the present author proved that these two factors are quite different from each other. The present author is of opinion that creatine phosphokinase-<I>PC</I>-ATP system added form without has not a remarkable relaxing effect, if not aided by some other factors. The mechanism of contraction-relaxation cycle in muscle was discussed.

• 社団法人 日本薬理学会の論文

著者

• 武田 文子

  東京大學醫學部藥理學教室

関連論文

• Two components of ATP-dependent relaxing factor in skeletal muscle
• Studies on relaxing factors in skeletal muscle

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