On the influence of Nitrolime upon the action of alcohol
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概要
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1) After the administration of Nitrolime, narcosis induced by intravenous injection of alcohol 'was remarkably strengthened, but the rate of disappearance of alcohol from blood was not significantly altered. 2) The experiments proved that immediately after injection of alcohol, there was much more alcohol content in brain and liver in the Nitrolime-treated animal (albino rat) than in the control, but contrariwise the content in muscle was found to be less. These experiments indicate that at least the intensified alcohol narcosis observed after Nitrolime+ alcohol can be explained as a result of changes in the distribution of alcohol in the tissues, but it is possible that some of the symptoms are due to other substances formed.
- 社団法人 日本薬理学会の論文