Studies on the metabolic change of nicotine in rabbit liver extract

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概要

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• Nicotine was determined either colorimetrically by the silicomolybdic acid method (<I>see</I> No. 7 of this Breviaria) and BrCN-anilin method or biologically by the isolated guinea pig intestine. The nicotine oxidation was studied by the manometric technique and also by Thunberg's method, and nicotyrine, an oxidation product, was determined by Ehrlich's pyrrole reaction, paperchro-matography and ultraviolet absorption spectra. The metabolic fate of nicotine in the rabbit liver extract was thus studied.

• 社団法人 日本薬理学会の論文

著者

• 竹内 道雄

  奈良縣立醫科大學藥理學教室

関連論文

• Br・CN反応による家兎尿中ニコチンの定量に就て
• Studies on the metabolic change of nicotine in rabbit liver extract
• Researches on the nicotine detoxication in rabbits with silicomolybdic acid method
• 白鼠に於けるニコチン連続投与実験

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