Studies of pyrogens (4)

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概要

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• In previous report <I>M. Kobayashi</I> has shown that the double-peaked time-temperature curve induced by the single injection of typhoid vaccine had been changed into a single-peaked one after repeated injections of the same pyrogen (<I>see</I> this Folia vol. 47, Breviaria nos. 10 and 11, 1951). The analogous facts were also proved in the case of the other pyrogens, e. g., starch, distilled water contaminated with air-born bacteria, coli vaccine and yeast extract, when applied the reduced amount of their injection. doses and also when injected repeatedly these pyrogens after heating, filtering and centrifuging. Such deformations of the fever curves are thought as concerned with the tolerance acquired by the animal against each pyrogen.

• 社団法人 日本薬理学会の論文

著者

• 藤竹 信英

  京都大學醫學部藥理學教室

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• Comparative studies on the curarimimeitc action of aromatic glucosides
• Studies of pyrogens (4)

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