Researches on the active principles in pearl-barley:(1). On the fatty oil contained in pearlbarley and on the pharmacological actions of palmitic acid
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概要
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Pearl-barley (<I>Coix Lacryma-jobi L. var. frumentacea Makino</I>) contains a fatty oil in 5.9-9.8 %. The main ingredient of unsaturated acids in the oil is _??_-octadecenic acid (Bp<SUB>5</SUB> 235<SUP>0</SUP>), -I call it <I>coixic acid</I>-and the saturated one, palmitic acid. The fatty oil has some effects on blood vessels and respiration, while palmitic acid has special effects on the sympathetic nerve endings of blood vessels, uterus and intestine just like ergotamine. It excites the respiration owing to its stimulant action on the respiratory center and on the motor nerve endings of respiratory tracts. It lessens the fatigue because of the stimulation of the motor activity. In addition it controls the outflow of urine, but has no action on heart directly.
- 社団法人 日本薬理学会の論文