動物細胞における糖輸送の調節
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概要
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Simple diffusion, sodium-dependent (active) and-independent (facilitated) transports are generally involved in hexose transport in animal cells. The regulation of facilitated hexose transport has been briefly reviewed. Hexose transport regulation is observed in most cells where the rate of hexose trans-fer is rate limiting for hexose metabolism. Experimental methods used for assay of transport activities and indentification of glucose carrier are very important to deduce any definitive conclusion regarding the regulation of glucose transport. Possible mechanisms of transport regulation might involve 1) control of the carrier synthesis and/or turn over 2) recycling of the carrier 3) modification of the carrier 4) interaction between the carrier and its lipid environment.
- 日本膜学会の論文