抗血栓材料を用いた血液浄化システムの開発
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概要
- 論文の詳細を見る
By combining a polyacrylonitrile (PAN) -polyethyleneoxide (PEO) membrane with ionically heparin-bound catheter, tubing, and module header, a totally antithrombogenic continuous ultrafiltration system (ACUS) was developed. Antithrombogenicity of PAN-PEO hollow fiber membrane was considered to be due to the presence of highly concentrated PEO near the inner surface of the membrane wich has a finely dispersed microstructure. ACUS was clinically applied to 24 patients without systemic anticoagulation and one PAN-PEO filter functioned for average 32 hrs without deteriorating their bleeding tendencies.
- 日本膜学会の論文