Clinical and Bacteriological Observations of Unclassified Acid-fast Bacilli Repeatedly Isorated During a Long Period of Time from Sputum of a Patient treated as Pulmonary Tuberculosis

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During a long period of one year and a half we have repeatedly isolated from the sputum of a patient who was treated as pulmonary tuberculosis a large quantity of bacilli which may be considered to be the so-called unclassified mycobacteria (nonphotochromogen).<BR>This acid-fast bacillus showed one or two bacteriological properties similar to those of mycobacterium tuberculosis, but it chiefly resembled to the saprophytic acid-bacillus in the natural world and its pathogenicity was slight for mice and almost negative for other animals such as guinea pigs, rabbits and hens.<BR>In order to diagnose the disease as a case caused by unclassified mycobacteria it is necessary that the increase and decrease of the bacteria should be closely connected with its clinical course. Indeed, our patient's discharging of acid-fast bacteria was parallel to his roentgengram and it became negative as his cavity disappeared.<BR>Although thcre is much left to be discussed about the origin or classification of unclassified mycobacteria, we understand our case indicates the possibility of the so-called unclassified mycobacteria's causing the lesions in lungs.<BR>Most of the cases so far reported as being caused by unclassified mycobacteria are serious ones, but if unclassified mycobacteria are to cause primary Pulmonary lesions, it may be inferred from out experimental cases that unclassified mycobacterial may be seen in slight cases rather than in serious ones.
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Clinical and Bacteriological Observations of Unclassified Acid-fast Bacilli Repeatedly Isorated During a Long Period of Time from Sputum of a Patient treated as Pulmonary Tuberculosis

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