D-2, 2'-(ETHYLENEDIIMINO)-DI-1-BUTANOL THERAPY ON PULMONARY DISEASE CAUSED BY "UNCLASSIFIED" MYCOBACTERIA (NONPHOTOCHROMOGEN)

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概要

• 論文の詳細を見る

• Three cases of pulmonary disease caused by nonphotochromogens who were successfuly treated by D-2, 2'-(Ethylenediimino)-di-l-butanol (Ebutol) were reported.<BR>As case 1 (completely resistant to 10γ Ebutol) was treated by the combination of Tetra cycline, Pyrazinamide and Ebutol, the clinical efficacy can not be attributed solely to Ebutol; In case 2 (incompletely resistant to 10γ Ebutol), a single drug regimen of Ebutol was quite effective as to bacilli conversion. In ease 3 (completely resistant to 1γ Ebutol), Ebutol was added to the combination of Cycloserine and 1314 TH which had been proved to be ineffective after the long term administration of 8 months. When bacilli reappeared after the interruption of Ebutol treatment, the drug was given again and prompt conversion was observed this time too. In case 1 and case 2 there was no change in X-ray finding, while in case 3 the regres sion of cavity was observed to certain extent.<BR>The clinical efficacy seems to depend more or less on the degree of resistance of bacilli to Ebutol.

• 一般社団法人 日本結核病学会の論文

著者

• BABA Makoto

  Tokyo National Chest Hospital

関連論文

• D-2, 2'-(ETHYLENEDIIMINO)-DI-1-BUTANOL THERAPY ON PULMONARY DISEASE CAUSED BY "UNCLASSIFIED" MYCOBACTERIA (NONPHOTOCHROMOGEN)

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