日本病理剖検輯報(1967〜1976)の集計による粟粒結核症の検討--特に発症および死亡要因について

概要

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The purpose of this report is to elucidate the present status of miliary tuberculosis. Material for this study was obtained by reviewing the annual of pathological autopsy cases in Japan, 1967-1976. Results were as follows: 1) Autopsy cases in patients who died of miliary tuberculosis within 10-year period were 940 cases. The aged were predominant. 492 cases were of males, 444 cases were of females and 4 cases were of unknown sexuality. Autopsy cases within the latter 5-year period increased compared with those within the former 5-year period. 2) Non-miliary tuberculosis was present in 47% of all cases and non-tuberculous disease was present in 25% of them. 3) Corticosteroids were used in 30% of them, which were noted as the predisposing factor. 4) Miliary tubercles were distributed in several organs. Concerning their distribution in various organs in relation to age of patients, no remarkable difference by age was seen in liver, spleen and kidney. On the contrary, meninges were involved more frequently in small children and loss in the aged, and the involvement of bone marrow was higher in the aged and lower in small children. 5) Only 12% of all cases were correctly diagnosed before autopsy. From the above results, importance of recognition of the changing feature of present miliary tuber culosis was emphasized.
一般社団法人日本結核病学会の論文