結核感染におけるcord factor の意義(第49回〔日本結核病学会〕総会特別講演)
スポンサーリンク
概要
- 論文の詳細を見る
Tuberculosis in man and laboratory animals is characterized by progressive wasting symptoms. As a causative agent of such intoxication signs in tuberculou8 infection, H. Bloch has reported the existence of a peculiar lipid toxin possessing a characteristic delayed toxicity for mice in petroleum-ether-extract of virulent <I>Mycobacterium tuberculosis.</I> Since the solvent extracted-bacilli have lost the property to grow in culture medium in forming "cords", this toxic lipid was named as "cord factor". The chemical structure of cord factor was subsequently identified as a 6, 6'-dimycoloyl-α, α'-D-trehalose.
- 一般社団法人 日本結核病学会の論文