Actinomyces菌体抽出多糖とC-Reactive Proteinの反応に関する研究

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概要

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• The reaction between polysaccharide extract from Actinomyces israelii (APS) and CRP-positive serum was studied.The results obtained are summarized as follows.1) CRP was precipitated with APS in the presence of Ca ions and 68-93% of it in serum. absorbed with APS.2) APS contained galactose, glucose, glucosamine, phosphate and choline in the molecular proportion of 4:1:2:1:1.3) CRP-APS precipitation was inhibited by various phosphate monoesters of low molecular weight, of which phosphoryl choline was the most active inhibitor.4) It was presum that choline-phosphate might be present at the end of APS-polymer, providing a site of reaction for APS.5) CRP was precipitated with polysaccharide extracts from A. israelii, A. odontolyticus and A. bovis, but not with that from A. naeslundii or A. viscosus.

• 日本細菌学会の論文

著者

• 永瀬 守

  新潟大学歯学部口腔外科学第1教室

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• Actinomyces菌体抽出多糖とC-Reactive Proteinの反応に関する研究

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