ぶどう球菌におけるスタフィロキナーゼ,ヌクレアーゼ,ヘモリジン産生におよぼすマイトマイシンCの影響

概要

論文の詳細を見る
Using Staphylococcus aureus, the effect of mitomycin C on the growth of cells and the production of staphylokinase (SAK), nuclease, and hemolysin was studied. The following results were obtained.1. All the strains investigated were lysed by addition of mitomycin C in the logarithmic phase at a concentration between 0.1 and 5.0γ/ml.2. The strains investigated could be divided into two groups, promotion and inhibition, as to the effect of mitomycin C on the production of SAK. The most remarkable effect was observed when mitomycin C had been added at a concentration of 0.5γ/ml to a staphylococcal culture with turbidity of KSR 150.3. In the case of the production of β-hemolysin, the strains could also be divided into two groups in the same sense of the word. No parallelism, however, was shown between the effect of mitomycin C on the production of SAK and that on the production of β-hemolysin.4. The production of nuclease and α-hemolysin was generally inhibited by addition of mitomycin C.
日本細菌学会の論文