Clostridium botulinumの毒素産生に関する実験的研究 (第2報)

概要

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1. With proteolytic group ofClostridium botulinum, marked decrease of turbidity of culture fluids is observed, suggesting the lysis of bacteria in the early stage of cultivation. On the other hand, the decrease of turbidity is not so conspicuous with non-proteolytic group. 2. The pH level of culture fluids attained by proteolytic group is always higher than that attained by non-proteolytic group. 3. The phenomenon of toxin activation by trypsin is obviously demonstrated with proteolytic type B, strain Lamanna, as well as with non-proteolytic type B, strain QC and type E, strains VH and Iwanai. On the other hand, the activation seems to be rather uncertain with non-proteolytic type C, strains Stockholm and 468 and type D, strain 1873, as well as proteolytic type A, strain 190.
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