ヒトの多形核白血球に食菌されたぶどう球菌の運命について

概要

論文の詳細を見る
Fate of the staphylococci that had been phagocytized by human polymorphonuclear leucocytes in vitro, were investigated and it was found that there existed quite a different attitude between Staphylococcus aureus and Staphylococcus epidermidis. Following the phagocytosis of Staphylococcus epidermidis by leucocytes, the viability of the cocci seemed to have been immediately influenced and most of them (98%) were found to be uncultivable within 24 hours. Morphological changes of the parasites such as swelling and difficulty in staining, occurred simultaneously without any noticeable damage on the part of the host cells (vital staining with trypan blue). On the other hand, in case of Staphylococcus aureus, the cocci showed hardly any change in terms of morphology, lasting 24 hours or longer. Most of them seemed to remain viable, which was demonstrated by cultivation. The parasites, however, had a mild influence to the cells. Consequently, there seemed to be a sort of balance maintained between the cocci and the human leucocytes.
日本細菌学会の論文