METHYLMALONIC ACIDURIA AND VITAMIN B12 DEFICIENCY IN THE RAT

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概要

• 論文の詳細を見る

• Methylmalonic aciduria is a metabolic defect characterized by an ex-cessive excretion of methylmalonic acid in the urine. The present paper reports the results obtained on rats fed a vitamin B12-deficient diet to which were administered propionate or the amino acids L-valine, L-isoleucine, L-methionine, L-threonine. Detection of metabolites was carried out by gas chromatography. The results obtained showed that besides propionate only L-valine and L-isoleucine cause an increase in the daily excretion of methylmalonic acid, while L-methionine and L-threonine have no effect on the rat.

• 財団法人 学会誌刊行センターの論文

著者

• Fiori A.

  Instituto Superiore Di Sanita Rome And Institute Of Biological Chemistry University Of Rome

• Costa M.

  Instituto Superiore di Sanita Rome and Institute of Biological Chemistry, University of Rome

• Orlando M.

  Instituto Superiore Di Sanita Rome And Institute Of Biological Chemistry University Of Rome

• Costa M.

  Instituto Superiore Di Sanita Rome And Institute Of Biological Chemistry University Of Rome

• FIORI A.

  Instituto Superiore di Sanità, Rome and Institute of Biological Chemistry, University

• ORLANDO M.

  Instituto Superiore di Sanità, Rome and Institute of Biological Chemistry, University

• COSTA M.

  Instituto Superiore di Sanità, Rome and Institute of Biological Chemistry, University

関連論文

• 3.シロネズミにおけるメチルマロン酸尿症とビタミンB_欠乏(JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY : 掲載論文要旨)
• METHYLMALONIC ACIDURIA AND VITAMIN B12 DEFICIENCY IN THE RAT

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