STUDIES ON THE INFLUENCE OF BIOTIN ON FOLATE METABOLISM IN ESCHERICHIA COLI B

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概要

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• Biotin has been shown to have no significant influence on the total levels of folates in Escherichia coil. Exogenous biotin caused a redistribution of folate derivatives favouring the intracellular accumulation of unconjugated methyltetrahydrofolates at the expense of conjugated formyltetrahydrofolates. The decreased levels of the conjugated folates in presence of biotin has been attributed to the observed lowering in the levels of folylconjugate synthetase. The availability of intracellular glutamic acid was not a limiting factor in the presence of biotin. The observed lowering in the concentration of intracellular methionine in the biotin grown cells has been discussed in the light of the decreased levels of conjugated folates in these cells.

• 財団法人 学会誌刊行センターの論文

著者

• Nair C.p.p

  Biochemistry And Food Technology Division Bhabha Atomic Research Center

• NORONHA J.

  Biochemistry and Food Technology Division, Bhabha Atomic Research Centre

関連論文

• 1.Escherichia coli Bにおける葉酸類の代謝に及ぼすビオチンの影響(JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY : 掲載論文要旨)
• STUDIES ON THE METABOLIC INTERRELATIONSHIP BETWEEN BIOTIN AND FOLIC ACID IN RATS
• STUDIES ON THE INFLUENCE OF BIOTIN ON FOLATE METABOLISM IN ESCHERICHIA COLI B

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