TERATOGENESIS OF THE HORSESHOE CRAB BY α-LIPOIC AMIDE (6, 8-THIOCTIC AMIDE) IN MARKETED VITAMIN TABLETS

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概要

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• Some marketed vitamin tablets induce defects and fusion of body segments and appendages in the developing horseshoe crab. α-Lipoic amide may be responsible for the induction, and the other vitamins are probably not directly responsible. α-Lipoic acid also induces the same malformations. It is presumed that α-Lipoic amide and α-lipoic acid inhibit thioldisulphide exchange and this inhibition disturbs the morphogenetic movement. As a result, the monsters may be induced by treatment with vitamin tablets.

• 財団法人 学会誌刊行センターの論文

著者

• 伊藤 富夫

  Department of Biology, Faculty of Education, Shizuoka University

関連論文

• An experimental study on the formation of body axes in embryos of the horseshoe crab, Tachypleus tridentatus
• Experimentally Induced Separation of Embryonic Area in the Eggs of the Horseshoe Crab
• TERATOGENESIS OF THE HORSESHOE CRAB BY α-LIPOIC AMIDE (6, 8-THIOCTIC AMIDE) IN MARKETED VITAMIN TABLETS

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