Casein phosphopeptide (CPP) enhances calcium absorption from the ligated segment of rat small intestine.

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概要

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• A casein phosphopeptide (CPP) was prepared from β-casein of cow's milk and the effect of this peptide on the absorption of calcium from a ligated segment of rat small intestine was investigated. CPP injected into a ligated loop of rat small intestine enhanced absorption of calcium from the loop and augmented the deposition of calcium in the femur. Furthermore, CPP inhibited the precipitation of calcium phos-phate in vitro, suggesting that this peptide enhances calcium absorption from the small intestinal lumen by increasing the concentration of soluble calcium. This new evidence confirms our previous hypothesis that CPP is an important factor in raising the availability of calcium in milk.

• 財団法人 学会誌刊行センターの論文

著者

• 佐藤 隆一郎

  Department of Agricultural Chemistry, The University of Tokyo

• 野口 忠

  Department of Agricultural Chemistry, The University of Tokyo

• 内藤 博

  Department of Agricultural Chemistry, The University of Tokyo

• 野口 忠

  Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo

• 内藤 博

  Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo

関連論文

• Effect of Lactose on Calcium Absorption from the Rat Small Intestine with a Non-Flushed Ligated Loop
• Casein phosphopeptide (CPP) enhances calcium absorption from the ligated segment of rat small intestine.
• Effects of insulin, amino acids and fasting on myofibrillar protein degradation in perfused hindquarters of rats.
• Regulation of plasma amino acid levels by perfusion of hindquarters of rats.

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