Effects of Excess Doses of a-Tocopherol on the Lipids and Function of Rainbow Trout Liver.

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概要

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• Rainbow trout (Oncorhynchus mykiss) were kept on diets containing three different α-tocopherol levels (0, 10, and 1, 000 mgt 100g diet) to investigate the effects of excess doses of α-tocopherol on the liver lipids and liver functions. Both the content of the lipids except α-tocopherol in the liver and the triglyceride ratio in total lipids were significantly increased by the diets containing 1, 000mg of α-tocopherol per 100g of diet. Many lipid droplets, 5-20μm in the diameter, were observed in the liver. The TBARS per milligrams of liver lipids was decreased by 1, 000-mg doses of α-tocopherol. GOT and GPT activity in serum were in the normal range regardless of the dose of α-tocopherol. From these data, it is considered that excess α-tocopherol promotes lipid accumulation enough to form droplets in the liver tissue, although liver function is not impaired.

• 財団法人 学会誌刊行センターの論文

著者

• TAKEUCHI Masaaki

  Laboratory of Marine Biochemistry, Faculty of Agriculture, Tohoku University

• Takeuchi Masaaki

  Laboratory Of Marine Biochemistry Faculty Of Agriculture Tohoku University

• Tokuda Masaharu

  Laboratory Of Marine Biochemistry Graduate School Of Agricultural Science Tohoku University

• TOKUDA Masaharu

  Laboratory of Marine Biochemistry, Faculty of Agriculture, Tohoku University

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• Effects of Excess Doses of a-Tocopherol on the Lipids and Function of Rainbow Trout Liver.

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