Direct Optical Resolution of (.+-.)-Biotin and (.+-.)-Epibiotin by a Reversed-Phase High-Performance Liquid Chromatography.

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概要

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• A first and efficient direct optical resolution of biotin dia-stereomers, (±)-biotin and (±)-epibiotin, was accomplished by a reversed phase high-performance liquid chromatography on cellulose tris (3, 5-di-methylphenylcarbamate) coated on silica-gel.

• 財団法人 学会誌刊行センターの論文

著者

• Yamano Toru

  Technology Development Department Takeda Chemical Industries

• AOKI Isao

  Technology Development Laboratories, Takeda Chemical Industries, Ltd.

• Takanohashi Kunio

  Technology Development Laboratories Takeda Chemical Industries Ltd.

• TAKANOHASHI Kunio

  Technology Developnent Laboratories, Takeda Chemical Industries, Ltd

• AOKI Isao

  Technology Developnent Laboratories, Takeda Chemical Industries, Ltd

関連論文

• A Practical Method for Optical Resolution of Recemic Alcohols or Esters via Lipase-Catalyzed Transformation and Sulfation
• Optical Resolution of a d-Biotin Chiral Intermediate by Use of Lipoprotein Lipase
• Direct Optical Resolution of (.+-.)-Biotin and (.+-.)-Epibiotin by a Reversed-Phase High-Performance Liquid Chromatography.

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