Fundamental studies on application of Nd-YAG laser to oral surgery. Hemostasis of movable oral mucous membrane.:Hemostasis of movable oral mucous membrane

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概要

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• The hemostatic effect of Nd-YAG laser on bleeding from movable mucous membranes of the oral cavity were studied.<BR>1) Adult dogs were medicated with 500 u/kg of Heparin, after which experimental bleeding wounds were made by excising the whole epithelium layer in a diameter of 4 mm on the tongue and buccal mucous membrane of dogs. The amount of bleeding before and after a one-shot irradiation of Nd-YAG laser to the above-mentioned experimental wounds was measured. The irradiation conditions of the Nd-YAG laser were set for a spot diameter at 4, 6, and 8 mm, a power density at 50, 100, 150, and 200 W/cm<SUP>2</SUP>, and a one-shot irradiation time at 2 seconds.<BR>As a result, the most optimal Nd-YAG laser-irradiation condition was considered to a 6 mm for the spot diameter and 200 W/cm<SUP>2</SUP> for the power density.<BR>2) The wound healing process of Nd-YAG laser-irradiated wounds was observed, and epithelization took 2 to 3 weeks. Cases that received about 1, 000 J of total Nd-YAG laser irradiation had more severe inflammation and tissue injury. Accordingly, the irradiation conditions or combined therapy should be considered to decrease the dosage as much as possible.<BR>3) Dogs were medicated with warfarin potassium adjusting its dosage so as to maintain the activity of thrombotest at 10-25%. With this preparation, similar experimental wounds as described above were made in two sites each of the tongue and buccal mucous membrane, and one wound was irradiated by Nd-YAG laser in spot diameter of 6 mm and a power density of 150-200 W/cm<SUP>2</SUP> until it reached complete hemostasis, while the other wound was sutured with 4-0 nylon thread.<BR>The degree of bleeding after the above-mentioned treatments was observed daily, and it was found that the group that was irradiated by the Nd-YAG laser showed significantly less bleeding than the group that was sutured.

• 社団法人 日本口腔外科学会の論文

著者

• 佐藤 耕治

  東京医科大学口腔外科学教室

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• Fundamental studies on application of Nd-YAG laser to oral surgery. Hemostasis of movable oral mucous membrane.:Hemostasis of movable oral mucous membrane

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