Experimental study on the tissue compatibility of SiC.
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Many dental implant materials used clinically have been subject to basic investigation. Recently, bioceramics have become the main materials used in dental implantation.<BR>This study notes that SiC is a non-hydrated material exhibiting superior hardness and lower weight. We have compared SiC with ZrO<SUB>2</SUB> in terms of cytotoxicity. And this is a comparative study with ZrO<SUB>2</SUB> in cytotoxity test and compatibility with soft tissue and bone.<BR>The results were as follows.<BR>1) Amount of dissolved Zr<SUP>4+</SUP>and Si<SUP>4+</SUP> ions were below 1.0 ppm.<BR>2) Cytotoxity was the same as that of ZrO<SUB>2</SUB> and glass, examined by the colony formation method, investigation of cell growth and SEM findings of the cell forms on the materials.<BR>3) SiC exhibited the same biocompatibility as ZrO<SUB>2</SUB>, as demonstrated by light and electron microscopic examination of subcutaneous implantation in the rats and femurs marrow space implantation in the rabbit.<BR>Results suggest that SiC is not cytotoxic and exhibits biocompatibility equal to that of ZrO<SUB>2</SUB>. The author therefore feels able to recommend the clinical use of SiC as soon as possible.
- 社団法人 日本口腔外科学会の論文
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- Experimental study on the tissue compatibility of SiC.