Morphological study concerning the interface of implants with demineralized dentin.

概要

論文の詳細を見る
Recently, hydroxyapatite which is made from apatite hydroxide has been clinically used in dental implants. It is known that hydroxyapatite functions as osteoconduction but not as osteoinduction. Thus, we applied demineralized dentin, a material having an effect of osteoinduction, in combination with hydroxyapatite dental implants. The author observed morphologically its mechanism in relation to bone attachment. Thirty mongrel dogs were used in this study. Their 3rd and 4th premolar teeth were extracted. After extraction, the teeth were cleaned by removal of the dental pulp and remnants of periodontal ligaments which remained on the cement surface. The extracted teeth were decalcified using Plank-Richlo method for 1 week, and rinsed overnight with distilled running water then sliced 100μm thick in a cryostat. The sliced dentins were implanted with Apaceram <SUP>®</SUP>. At 3 days, 1 and, 2 weeks, 1, 3 and 6 months after operation, the experimental dogs were sacrificed and specimens were fixed. The osteoid was observed around the demineralized dentin 3 days after operation. On days 7 and 14 after operation, new bone accumulated around the implant. On day 7, the demineralized dentin was enclosed by new bone. On day 30, demineralized dentin was resorbed and replaced by new bone with the passage of time. The newly formed bone was found to be ankylosed with the implant.
社団法人日本口腔外科学会の論文