A case with multiple abnormalities born to epileptic mother taking anticonvulsant drugs. Anticonvulsant embryopathy.:anticonvulsant embryopathy
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概要
- 論文の詳細を見る
We experienced a case of supposed anti-convulsant embryopathy, which is a comparatively rare disease. We would like to supply arguments for its diagnosis and also to make examination of the operative time for cleft palate associated with this case.<BR>The case is a 7-month-old male infat without siblings, whose parents' blood relative and lineages deny teratogenic diseases, His moher, who was diagnosed as epilepsy at age 9, has so far been taking anticonvulsant drugs (phenobar, sodium valporate, primidon, sultiame) without interruption during the pregnancy. The pregnant course was uneventful except for unique petit mal in gestational months 4 and 5 each but prenatal growth deficiency led to cesarean section at gestational age, 37 weeks and 3 days. The baby weighed 2, 100g (SFD) at birth, and immediately thereafter, barbiturate withdrawal syndrome appeared and multiple anomalies (wide fontanele, low-set ears, hypertelorism, ptosis of eyelids, cleft palate, contracture palmarls, short fingers, clubbed penis, small scrotum, inguinal hernias, undescended testes, etc). were noted. Thereafter, the infant needed longterm internal medical control becaue of postnatal hypognesis and psychomotor retardation. At age 3 (BW, 8, 160g), the infant received palatoplasty, intra-and post-operative courses being uneventful. Now, one year postoperatively, the infant (aged 4 years and weighing 9, 720g) still presents self-dysbasia and allopliasia in thecourse of observation.
著者
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今井 裕
独協医科大学口腔外科学講座
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朝倉 昭人
独協医科大学口腔外科学教室
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坂元 晴彦
独協医科大学口腔外科学教室
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岡部 清幸
独協医科大学口腔外科学教室
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鈴木 克昌
独協医科大学口腔外科学教室
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横倉 幸弘
独協医科大学口腔外科
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細谷 玲子
独協医科大学口腔外科
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永島 知明
独協医科大学口腔外科
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豊橋 真成
独協医科大学口腔外科
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豊橋 真成
独協医科大学口腔外科学教室
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横倉 幸弘
独協医科大学口腔外科学教室
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永島 知明
独協医科大学口腔外科学教室
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坂元 晴彦
独協医科大学口腔外科
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細谷 玲子
独協医科大学口腔外科学教室
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朝倉 昭人
独協医科大学口腔外科
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