上唇に発生した稀有なる形質細胞腫の1例

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Plasmacytoma is the disease with tumor-like growth of plasma cell or of their cognate, and often generates in the bone tissues of the entire body as multiple myeloma. Also, unusually, it develops in soft tissue as extramedullary plasmacytoma.<BR>We present a case of extramedullary plasmacytoma which originated in the upper lip, which might be the first case to be reported in Japan.<BR>A 33-year-old woman had been aware of the tumor developing on the inner side of upper lip for two months, and then visited us with a complaint of its discomfort. Upon pathological examination, this tumor was completely excised and was suspected of being plasmacytoma.<BR>General examinations followed, which denied the possibility of multiple myeloma. Furthermore, we investigated an excised sample by immunohistological examination, and identified it as extrameduallary plasmacytoma with IgA and κ-chain. In order to prevent its recurrence and metastasis, chemotherapy with Cyclophosphamide, Vincristine, Doxorubicin, and Predonisolone was done, and after a year and two months she is still in excellent condition.