口唇口蓋裂による顎変形症の治療に関する実験的研究-人工的顎口蓋裂部への新鮮自家肋骨移植について-

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The surgical correction of secondary dentofacial deformities associated with cleft palate, in some cases, encounter problems such as difficulty in positioning of osteotomized maxillary bony segments, postoperative relapse with unstable maxillary segments especially in the case of palatal expansion.Alleviation of tension in palatal soft tissue and bone grafting into the cleft alveolus and palate are believed to be essential in solving these problems.<BR>Experimental models with cleft alveolus and palate were produced surgically in adult Macaca fuscata monkeys, and these defects were repaired with mucoperiosteal flap.Repeated elevations of mucoperiosteum were performed in creating the cleft alveolus and palate, repairing them, and grafting of autologous cortico-cancellous bone block into the bony clefts.Bone healing was studied for up to 6 months using contactmicroangiography, fluorescence microscopic and histologic examination.<BR>Results of these clinically analogous studies indicate that the remodeling procedure of grafted cortico-cancellous bone block is obviously delayed in surgically damaged palatal side. In addition, differences in bone healing were recognized by the recipient site and depending on the grafting fashion.
社団法人日本口腔外科学会の論文