歯原性嚢胞における上皮増殖能の比較研究

概要

論文の詳細を見る
The purpose of this study was to compare the proliferative activity of epithelia in odontogenic keratocysts (5 cases), follicular dental cysts (5 cases) and radicular cysts (5 cases) by using nucleolar organizer regions (Ag-NORs) and proliferating cell nuclear antigen (PCNA) in conjunction with computer-assisted imageanalysis. The following results were obtained:<BR>The mean numbers of Ag-NORs were 2.03±0.45 in odontogenic keratocysts, 1.38±0.16 in follicular dental cysts and 1.45±0.21 in radicular cysts. The difference in the mean number of Ag-NORs between odontogenic keratocysts and the other two types of cysts was statistically significant (P<0.05).<BR>PCNA-positive scores were 20.3±10.3% in odontogenic keratocysts, 11.7±9.9% in follicular dental cysts and 11.5±7.3% in radicular cysts. The difference in PCNA-positive score between odontogenic keratocysts and the other two types of cysts was also significant (P<0.05).<BR>However, there was no correlation between the mean number of Ag-NORs and PCNApositive score. Thus, the epithelia of odontogenic keratocysts had high proliferative activity from the viewpoint Ag-NORs and PCNA.
社団法人日本口腔外科学会の論文