113Sn利用による弗化第1錫の歯牙う蝕に関する研究 : 塗布条件並びにpHによる離脱の研究

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Studies were conducted, from the standpoint of tin, by making use of radioactive tin-113, on the anti-corrosive effect of stannous fluoride on the enamel of an extracted tooth. The radioactive stannous fluoride was produced by leaving a large quantity of 113SnF2 mixed with a very small amount of 113SnCl2 as it was for 3 hours, in order to transform 113SnCl2 obtained into 113SnF2. Therefor was used the substitution equivalent to effect halogen ion of fluorine (F) and chlorine (Cl) adhering to tin ion (Sn++) of both elements. As the experimental item, the conditions and adhering status of stannous fluoride at the time of application were measured by the well-type scintillation counter from the aspect of radioactivity, while the domain of its segregation was observed by auto-radiography. And, measurement was also made on the segregation amount of tin in the acid-alkali solution. The results obtained were as follows : 1. It is optimum to apply the ointment at 8% in concentration for 2-3 hours. 2. The tin of stannous fluoride adheres evenly to the surface of healthy and normal enamel, especially much to the carious and damaged parts. 3. The segregation of tin caused by the acid-alkali solution is more violent as acid is stronger, and a large amount of segregation of tin in pH 5.0-pH 3.0 has been observed since the early stage.
有限責任中間法人日本口腔衛生学会の論文