Relationship between Kyphosis and Barretts Esophagus in Japanese Patients
スポンサーリンク
概要
- 論文の詳細を見る
Background Kyphosis is a risk factor for the presence of hiatal hernia, which is a strong predictor of Barretts esophagus. However, the association between kyphosis and Barretts esophagus has not yet been clarified. To investigate this relationship, the Cobb angle, a marker of kyphosis, was measured in patients with and without Barretts esophagus. Methods From January 2006 to December 2010, 26 patients with long-segment Barretts esophagus (LSBE) were retrospectively enrolled. As the comparative groups, 100 consecutive patients with short-segment Barretts esophagus (SSBE) and 100 consecutive control patients without Barretts esophagus were also enrolled in this study. Cobb angles were measured on lateral chest radiographs, and kyphosis was defined as a Cobb angle of greater than 50°. Kyphosis, along with other patient characteristics, were evaluated as possible predictors for SSBE and LSBE. Results The mean Cobb angles in the non-BE, SSBE, and LSBE groups were 31.6° (95% CIs, 29.3°-33.9°), 34.8° (32.1°-37.4°) and 49.4° (44.9°-53.9°), respectively. Statistically significant differences were found between the LSBE and the other 2 groups (p<0.001). The mean Cobb angles were 33.3°±12.4° and 37.0°±14.1°, respectively in patients without and with hiatal hernia (p=0.039). Predictors for Barretts esophagus of any length were erosive esophagitis and hiatal hernia. Kyphosis had the highest odds ratio for the presence of LSBE (OR, 1.50; 95% CI, 1.05-1.94; p=0.033). Other predictors were hiatal hernia and the absence of Helicobacter pylori infection. Conclusion Kyphosis is a risk factor for the presence of LSBE in Japanese patients.
著者
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ISHIHARA Shunji
The Second Department of Internal Medicine
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KINOSHITA Yoshikazu
The Second Department of Internal Medicine
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Yuki Takafumi
Division Of Endoscopy Shimane University Hospital
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Amano Yuji
Division Of Endoscopy Shimane University Hospital
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Ishihara Shunji
The Second Department of Internal Medicine, Shimane University, Faculty of Medicine, Japan
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Uno Goichi
Division of Endoscopy, Shimane University Hospital, Japan
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Oka Akihiko
The Second Department of Internal Medicine, Shimane University, Faculty of Medicine, Japan
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Ishimura Norihisa
The Second Department of Internal Medicine, Shimane University, Faculty of Medicine, Japan
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