シクロテンのマンニッヒ反応 : 3, 5-Dimethyl-2-cyclopenten-2-ol-1-oneの新合成法

概要

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An extensive study has been made on the synthesis of a new flavor (3, 5-dimethyl-2-cyciopenten-2-ol-1-one). Cyclotene reacts with formalin and morpholine to give the corresponding Mannich base (3-methyl-5-morpholinomethyl-2-cyclopenten-2-ol-1-one). The Mannich derivative was treated with zinc and glacial acetic acid to afford 3, 5-dimethyl-2-cyclopenten-2-ol-1-one which had a soft caramel-like odor. This compound will be favorable for food flavor.