小児に発生した声門下顆粒細胞腫例

概要

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We report a rare pediatric case of granular cell tumor (GCT) arising from the subglottis. A 10-year-old boy seen for hoarseness was found in flexible fiberscopic examination to have a submucosal mass below the left vocal cord. The tumor was completely removed in direct laryngoscopy under general anesthesia. Histologically, the tumor showed the proliferation of large cells with abundant eosinophilic granular cytoplasm and oval nuclei and a surface entirely covered by stratified squamous epithelium. Immunohistochemically, S-100 protein was positive. Although a polypoid mass was seen 3 months after surgery, reexcision confirmed it to be postoperative granulation eliminating the possibility of recurrence. He remains free of recurrence 29 months after surgery. The number of pediatric laryngeal GCT reported appears to be increasing, possibly due to progress in indirect laryngoscopic devices.