Successful Treatment of Necrotizing Fasciitis in an Upper Extremity Caused by Clostridium perfringens after Bone Marrow Transplantation
スポンサーリンク
概要
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We report a 47-year-old man with acute leukemia who survived a severe case of necrotizing fasciitis caused by Clostridium perfringens involving his right upper extremity. On day 5 after stem cell transplantation, progressive local tissue necrosis led to septicemia and disseminated intravascular coagulation. Early diagnosis and prompt initiation of appropriate therapy, including surgical debridement and broad-spectrum antibiotics, were crucial. A recombinant thrombomodulin might have not only resolved the coagulation problem but also prevented multiple organ failure associated with the systemic inflammatory response.
著者
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Fujishima Naohito
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan
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Hirokawa Makoto
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan
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Saitoh Hirobumi
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan
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Ito Mitsugu
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan
関連論文
- Thrombotic Thrombocytopenic Purpura with Severe ADAMTS-13 Deficiency in a Patient with Antiphospholipid Antibodies and Charcot-Marie-Tooth Disease
- Successful Treatment of Necrotizing Fasciitis in an Upper Extremity Caused by Clostridium perfringens after Bone Marrow Transplantation