False-Positive Human Immunodeficiency Virus Antibody Test and Autoimmune Hemolytic Anemia in a Patient with Angioimmunoblastic T-Cell Lymphoma

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概要

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• A 44-year-old woman was admitted with generalized lymphadenopathy, which was diagnosed as angioimmunoblastic T-cell lymphoma (AITL). The patient showed autoimmune hemolytic anemia (AIHA), polyclonal hypergammaglobulinemia and a high antinuclear antibody titer. Moreover, a human immunodeficiency virus (HIV)-1/2 screening test using the particle agglutination method was reactive. After chemotherapy for AITL, the AIHA was eliminated, and the false-positive HIV results were no longer detected. Autoimmunity associated with AITL is the likely cause of the cross-reaction with HIV and the AIHA. It is important to recognize that the cross-reaction with HIV can be a potential complication in AITL as well as AIHA.

著者

• Fujishima Masumi

  Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan

• Kameoka Yoshihiro

  Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan

• Hirokawa Makoto

  Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan

• Ichinohasama Ryo

  Division of Hematopathology, Tohoku University Graduate School of Medicine, Japan

• Saitoh Hirobumi

  Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan

関連論文

• False-Positive Human Immunodeficiency Virus Antibody Test and Autoimmune Hemolytic Anemia in a Patient with Angioimmunoblastic T-Cell Lymphoma

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